Expression of matrix metalloproteinase-1, -9, -13, and tissue inhibitor of metalloproteinases-1 in basal cell carcinomas of the eyelid

@article{Zlatarova2011ExpressionOM,
  title={Expression of matrix metalloproteinase-1, -9, -13, and tissue inhibitor of metalloproteinases-1 in basal cell carcinomas of the eyelid},
  author={Zornitsa I. Zlatarova and Ekaterina B. Softova and Klara G. Dokova and Elisabeth M. Messmer},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2011},
  volume={250},
  pages={425-431}
}
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) function in the remodelling of the extracellular matrix in morphogenesis, angiogenesis, tissue repair, and tumor invasion. Elevated levels of distinct MMPs in tumor tissue are related to worse prognosis. However, no overall consistent pattern of expression in human cancer has been identified. The aim of the present study was to evaluate the expression of MMP-1, -9, -13 and TIMP-1 in tumor epithelial cells and… CONTINUE READING