Expression of manganese superoxide disumutase influences chemosensitivity in esophageal and gastric cancers.

@article{Izutani2002ExpressionOM,
  title={Expression of manganese superoxide disumutase influences chemosensitivity in esophageal and gastric cancers.},
  author={Ryo Izutani and Michio Kato and Satoshi Asano and Motohiro Imano and Harumasa Ohyanagi},
  journal={Cancer detection and prevention},
  year={2002},
  volume={26 3},
  pages={213-21}
}
The purpose of this study was to examine whether the increased sensitivity of cancer cells to adriamycin (ADM), which is known to produce superoxide radicals, was brought through suppressed manganese superoxide disumutase (MnSOD) expression in the presence of transforming growth factor beta1 (TGFbeta1). T.T., MKN28, and MKN45 cell lines were treated with… CONTINUE READING