Expression of major gap junction connexin types in the working myocardium of eight chordates.

Abstract

The alpha1 connexin (connexin43) is regarded as the major gap junction protein of the myocardium because it predominates there in mammals. Here, we show that it is not the major connexin of the working myocardium in non-mammalian vertebrates, which instead express beta1-like connexins homologous to mammalian connexin32. A phylogenetic series of hearts was… (More)

Topics

  • Presentations referencing similar topics