Expression of macrophage inflammatory protein-2 and KC mRNA in pulmonary inflammation.

@article{Huang1992ExpressionOM,
  title={Expression of macrophage inflammatory protein-2 and KC mRNA in pulmonary inflammation.},
  author={Shengdong Huang and Joseph D. Paulauskis and John Godleski and Lester Kobzik},
  journal={The American journal of pathology},
  year={1992},
  volume={141 4},
  pages={981-8}
}
This study sought to test the hypothesis that expression of mRNA for two cytokines, macrophage inflammatory protein-2 (MIP-2) and the KC gene product, is induced in rat lung cells during inflammatory responses in vitro and in vivo. Macrophage inflammatory protein-2 and KC are members of the platelet-factor 4 (PF-4) cytokine superfamily that cause marked neutrophil chemotaxis and activation in vitro. To investigate expression of the genes for MIP-2 and KC in rat models of lung injury, cDNA… CONTINUE READING