Expression of mRNAs for alpha-fetoprotein (AFP) and albumin and incorporation of AFP and docosahexaenoic acid in baboon fetuses.

@article{Naval1992ExpressionOM,
  title={Expression of mRNAs for alpha-fetoprotein (AFP) and albumin and incorporation of AFP and docosahexaenoic acid in baboon fetuses.},
  author={Javier Naval and Miguel Calvo and Jo rge Laborda and P Dubouch and Monique Frain and J. M. Sala-Trepat and J. A. Uriel},
  journal={Journal of biochemistry},
  year={1992},
  volume={111 5},
  pages={649-54}
}
alpha-Fetoprotein and albumin, two members of a multigene family, reversibly bind fatty acids with high affinity. The origin of alpha-fetoprotein (AFP) and albumin present in fetal tissues other than the liver and yolk sac is a subject of controversy. In this work, we have searched for the presence of the albumin and AFP mRNA molecules in different fetal organs of the baboon (Papio cinocephalus), using a highly sensitive gel-blot hybridization assay with human albumin and AFP cDNA probes. Large… CONTINUE READING