Expression of mRNA and functional alpha(1)-adrenoceptors that suppress the GIRK conductance in adult rat locus coeruleus neurons.

@article{Osborne2002ExpressionOM,
  title={Expression of mRNA and functional alpha(1)-adrenoceptors that suppress the GIRK conductance in adult rat locus coeruleus neurons.},
  author={Peregrine B Osborne and Maria Vidovic and Billy Chieng and Caryl E. Hill and Macdonald J Christie},
  journal={British journal of pharmacology},
  year={2002},
  volume={135 1},
  pages={226-32}
}
1. Locus coeruleus neurons in adult rats express binding sites and mRNA for alpha(1)-adrenoceptors even though the depolarizing effect of alpha(1)-adrenoceptor agonists on neonatal neurons disappears during development. 2. In this study intracellular microelectrodes were used to record from locus coeruleus neurons in brain slices of adult rats and reverse… CONTINUE READING