Expression of lynx1 in developing lung and its modulation by prenatal nicotine exposure

  title={Expression of lynx1 in developing lung and its modulation by prenatal nicotine exposure},
  author={Harmanjatinder S. Sekhon and Pingfang Song and Yibing Jia and J. C. Lindstrom and E. R. Spindel},
  journal={Cell and Tissue Research},
The expression of nicotinic acetylcholine receptors (nAChR) in fetal lung suggests maternal smoking during pregnancy effects newborn lung structure and function by the direct interaction of nicotine with nAChR in the developing lung. The recent identification of the lynx1 nAChR modulator protein in nicotinic neurons in the brain suggests that lynx1 may be similarly expressed in the lung. To study this, cDNAs encoding lynx1 were cloned from rhesus monkey lung. The temporal expression of lynx1… CONTINUE READING


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Spindel ER (2002b) Lynx1, choline acetyltransferase and nicotinic acetylcholine receptor (nAChR) expression in bronchioalveolar carcinoma

  • HS Sekhon, JA Keller, P Song, CL Corless, N Olson, J Lindstrom
  • Am Assoc Cancer Res 43:A2569 (93rd Annual Meeting…
  • 2002
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