Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome.

@article{Cui2003ExpressionOL,
  title={Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome.},
  author={Wei Cui and Ying Fan and Wei Wu and Feng Zhang and Jun-ying Wang and A. J. Ni},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2003},
  volume={37 6},
  pages={857-9}
}
In a cohort of 38 patients with severe acute respiratory syndrome (SARS), we observed leukopenia in 47% of patients, lymphopenia in 84%, and T lymphopenia in 95%. CD4(+) T lymphocyte levels were reduced in 100% of patients, CD8(+) T lymphocyte levels were reduced in 87%, B lymphocyte levels were reduced in 76%, and natural killer cell levels were reduced in 55%. Our data suggested that these patients' immune systems were impaired during the course of SARS. The absolute counts of lymphocyte… CONTINUE READING

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