Expression of leukemia inhibitory factor (LIF) and LIF receptor (LIF-R) in the human adrenal cortex: implications for steroidogenesis.

@article{Bamberger2000ExpressionOL,
  title={Expression of leukemia inhibitory factor (LIF) and LIF receptor (LIF-R) in the human adrenal cortex: implications for steroidogenesis.},
  author={Ana-maria Bamberger and Heinrich Maria Schulte and Andreas Wullbrand and Rudolf Jung and Frank Ulrich Beil and Christoph M. Bamberger},
  journal={Molecular and cellular endocrinology},
  year={2000},
  volume={162 1-2},
  pages={145-9}
}
It is well established that steroidogenesis in the adrenal cortex is regulated by extraadrenal factors, such as ACTH and angiotensin II. However, over the last years, it has become increasingly clear that paracrine and autocrine mechanisms are also important for steroid synthesis in the adrenal gland. The current study was designed to analyze whether the pleiotropic cytokine leukemia inhibitory factor (LIF) and/or its receptor (LIF-R) are expressed in the normal human adrenal cortex, and… CONTINUE READING
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