Expression of lectin-like oxidized low-density lipoprotein receptor-1 in allografted hearts.

@article{Suga2004ExpressionOL,
  title={Expression of lectin-like oxidized low-density lipoprotein receptor-1 in allografted hearts.},
  author={Michio Suga and Tatsuya Sawamura and Tatsuya Nakatani and Soichiro Kitamura},
  journal={Transplantation proceedings},
  year={2004},
  volume={36 8},
  pages={2440-2}
}
The pathogenesis of posttransplant coronary artery disease, which is thought to be a major form of chronic rejection after cardiac transplantation, is not fully understood. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) on endothelial cells induces reduction of NO release and up-regulation of adhesion molecules, thereby contributing to the… CONTINUE READING