Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level.

@article{Lacey1994ExpressionOL,
  title={Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level.},
  author={Stephen W. Lacey and Hassan Y Naim and Ronald R Magness and M J Gething and Joseph F. Sambrook},
  journal={The Biochemical journal},
  year={1994},
  volume={302 ( Pt 3)},
  pages={929-35}
}
Lactase-phlorizin hydrolase (LPH) is expressed on the intestinal brush border and is responsible for the hydrolysis of lactose, the chief sugar in mammalian milk. The enzyme activity of LPH peaks soon after birth in most mammals and declines to much lower levels before adolescence. The molecular basis of this pattern of expression has not been clearly established. We have measured relative amounts of LPH mRNA in intestine from sheep with ages across a developmental spectrum, including third… CONTINUE READING

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Molecular Cloning: A Laboratory Manual, 2nd edn., vols

  • J. Sambrook, E. F. Fritsch, T. Maniatis
  • 1989

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