Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs.

@article{Li1998ExpressionOK,
  title={Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs.},
  author={Zhongqi Li and Cynthia L Kelley and Fort Collins and D A Rouse and Sheldon L. Morris},
  journal={The Journal of infectious diseases},
  year={1998},
  volume={177 4},
  pages={1030-5}
}
The molecular mechanisms associated with the pathogenesis of tuberculosis are not well understood. The present study evaluated the role of catalase-peroxidase as a potential virulence factor for Mycobacterium tuberculosis. Growth and persistence of M. tuberculosis H37Rv in intravenously infected BALB/ c mice were compared with katG-deleted, isoniazid… CONTINUE READING