Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells.

@article{Hellerbrand1996ExpressionOI,
  title={Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells.},
  author={Hellerbrand and Stewart C. Wang and Hidekazu Tsukamoto and David Brenner and Richard A. Rippe},
  journal={Hepatology},
  year={1996},
  volume={24 3},
  pages={670-6}
}
The hepatic stellate cell (HSC), following a fibrogenic stimulus, is transformed from a quiescent to an activated cell. HSC activation results in numerous changes in cellular morphology, cellular metabolism, and in the pattern of gene expression. Many of the changes that are observed in activated HSCs in animal models of hepatic fibrosis are also seen when these cells are activated by culturing on plastic. These changes include morphological changes to a myofibroblast-like cell with the… CONTINUE READING
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