Expression of interleukin (IL)-1β and IL-1 receptors genes in the hypothalamus of anoestrous ewes after lipopolysaccharide treatment.

@article{Herman2010ExpressionOI,
  title={Expression of interleukin (IL)-1β and IL-1 receptors genes in the hypothalamus of anoestrous ewes after lipopolysaccharide treatment.},
  author={Andrzej Przemysław Herman and Tomasz Misztal and Anna Herman and Dorota Tomaszewska-Zaremba},
  journal={Reproduction in domestic animals = Zuchthygiene},
  year={2010},
  volume={45 6},
  pages={
          e426-33
        }
}
This study was designed to determine the effect of intravenous lipopolysaccharide (LPS) administration on the secretion of interleukin (IL)-1β and IL-1 receptors (IL-1Rs) gene expression in the hypothalamus of anoestrous ewes. Gene expression of IL-1β and its receptors was assayed by the real-time polymerase chain reaction. The expression of IL-1β in the hypothalamus was detected using Western blot. Our results showed that IL-1β mRNA is transcribed in the ovine hypothalamus. Lipopolysaccharide… CONTINUE READING
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