Expression of interferon regulatory factor 4 in chronic myeloid leukemia: correlation with response to interferon alfa therapy.

@article{Schmidt2000ExpressionOI,
  title={Expression of interferon regulatory factor 4 in chronic myeloid leukemia: correlation with response to interferon alfa therapy.},
  author={Michele M Schmidt and Andreas Hochhaus and Sven A. K{\"o}nig-Merediz and Cornelia Brendel and J Proba and Georg J Hoppe and Burghardt Wittig and Gerhard Ehninger and R{\"u}diger Hehlmann and Andreas Neubauer},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2000},
  volume={18 19},
  pages={3331-8}
}
PURPOSE Mice experiments have established an important role for interferon regulatory factor (IRF) family members in hematopoiesis. We wanted to study the expression of interferon regulatory factor 4 (IRF4) in various hematologic disorders, especially chronic myeloid leukemia (CML), and its association with response to interferon alfa (IFN-alpha) treatment in CML. MATERIALS AND METHODS Blood samples from various hematopoietic cell lines, different leukemia patients (70 CML, 29 acute myeloid… CONTINUE READING

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