Expression of indoleamine 2,3-dioxygenase in human corneal cells as a local immunosuppressive factor.

Abstract

PURPOSE To identify the localization of indoleamine 2,3-dioxygenase (IDO) in human corneal cells and to evaluate its functional ability as a local immunosuppressive factor. METHODS The expression profile of IDO was identified in primary cultures of human corneal cells (fibroblasts, epithelial cells, endothelial cells) by RT-PCR and Western blot analysis… (More)

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