Expression of iNOS mRNA associated with suppression of colonic contraction in rat colitis.

@article{Lundberg2006ExpressionOI,
  title={Expression of iNOS mRNA associated with suppression of colonic contraction in rat colitis.},
  author={Sofie Lundberg and Mikael Holst and Per M Hellstr{\"o}m},
  journal={Acta physiologica},
  year={2006},
  volume={187 4},
  pages={
          489-94
        }
}
AIM Nitric oxide (NO) synthesis and inducible NO synthase (NOS) expression are increased in colon of patients with inflammatory bowel disease (IBD) and associated with decreased contractility. The aim was to investigate which subtype of NOS that is activated in experimental colitis. METHODS Experimental colitis was induced in Sprague-Dawley rats by Escherichia coli endotoxin. Expression of different subtypes of NOS was compared in normal and inflamed colon using reverse transcriptase… CONTINUE READING

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