Expression of iNOS mRNA associated with suppression of colonic contraction in rat colitis
@article{Lundberg2006ExpressionOI, title={Expression of iNOS mRNA associated with suppression of colonic contraction in rat colitis}, author={S. Lundberg and M. Holst and P. Hellstr{\"o}m}, journal={Acta Physiologica}, year={2006}, volume={187} }
Aim: Nitric oxide (NO) synthesis and inducible NO synthase (NOS) expression are increased in colon of patients with inflammatory bowel disease (IBD) and associated with decreased contractility. The aim was to investigate which subtype of NOS that is activated in experimental colitis.
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References
SHOWING 1-10 OF 45 REFERENCES
Induction of nitric oxide synthase in rat intestine and its association with tissue injury
- Biology, Medicine
- Agents and Actions
- 2005
- 16
- Highly Influential
Toxic dilatation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase.
- Biology, Medicine
- The American journal of physiology
- 1996
- 77
Relative contributions of NOS isoforms during experimental colitis: endothelial-derived NOS maintains mucosal integrity.
- Biology, Medicine
- American journal of physiology. Gastrointestinal and liver physiology
- 2004
- 71
- PDF
Nitric oxide synthase activity in ulcerative colitis and Crohn's disease
- Medicine
- The Lancet
- 1993
- 453
- Highly Influential
Induction of nitric oxide synthase in colonic smooth muscle from patients with toxic megacolon.
- Medicine
- Gastroenterology
- 1995
- 108
Implication of TNF-alpha convertase (TACE/ADAM17) in inducible nitric oxide synthase expression and inflammation in an experimental model of colitis.
- Chemistry, Medicine
- Cytokine
- 2001
- 66
Functional activity and expression of inducible nitric oxide synthase (iNOS) in muscle of the isolated distal colon of mdx mice
- Biology, Medicine
- Muscle & nerve
- 2004
- 10
Increased disease activity in eNOS-deficient mice in experimental colitis.
- Medicine
- Free radical biology & medicine
- 2003
- 61
Increased Expression of Inducible Nitric Oxide Synthase in Circulating Monocytes from Patients with Active Inflammatory Bowel Disease
- Biology, Medicine
- Scandinavian journal of gastroenterology
- 2002
- 40
- PDF
LPS-induced muscularis macrophage nitric oxide suppresses rat jejunal circular muscle activity.
- Biology, Medicine
- American journal of physiology. Gastrointestinal and liver physiology
- 1999
- 165
- Highly Influential