Expression of human telomerase reverse transcriptase in gastrointestinal stromal tumors occurs preferentially in malignant neoplasms.

@article{Sabah2004ExpressionOH,
  title={Expression of human telomerase reverse transcriptase in gastrointestinal stromal tumors occurs preferentially in malignant neoplasms.},
  author={Muna Sabah and Robert J. Cummins and M. Sc. Sally WilsonProject Leader and Elaine B Kay},
  journal={Human pathology},
  year={2004},
  volume={35 10},
  pages={1231-5}
}
Telomerase is expressed in many human cancers and cell lines and is thought to contribute to their immortality. To date, little is known about the expression of telomerase in nonepithelial tumors. The objective of this study was to evaluate the expression of human telomerase reverse transcriptase (hTERT) in gastrointestinal stromal tumors (GISTs). Twenty-three GISTs (9 low malignant potential, 10 primary malignant, and 4 intra-abdominal recurrences) were evaluated for hTERT expression by using… CONTINUE READING