Expression of human catalase in acatalasemic murine SV-B2 cells confers protection from oxidative damage.

@article{LindauShepard1993ExpressionOH,
  title={Expression of human catalase in acatalasemic murine SV-B2 cells confers protection from oxidative damage.},
  author={Barbara A Lindau-Shepard and Jacquelin B. Shaffer},
  journal={Free radical biology & medicine},
  year={1993},
  volume={15 6},
  pages={581-8}
}
Reactive oxygen species have been implicated in aerobic organisms as causative agents in damage to DNA, proteins, and lipids. Catalase is a major enzyme in the defense against such oxidant damage. To determine whether increased catalase expression confers greater resistance to oxidant stress, a eukaryotic expression vector harboring a human catalase cDNA clone was constructed. Acatalasemic murine fibroblasts were then co-transfected with that catalase expression vector and pSV2-neo, and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…