Expression of human CXCR2 in murine neutrophils as a model for assessing cytomegalovirus chemokine vCXCL-1 function in vivo.

Abstract

Human cytomegalovirus (CMV) (Toledo strain) produces a potent chemokine (vCXCL-1) that specifically recognizes human (Hu)CXCR2, one of two human CXCL8 (IL8) receptors found on peripheral blood neutrophils. Thioglycollate-elicited neutrophils from BALB/c mice failed to respond to vCXCL-1 while retaining the capacity to respond to known murine (Mu) CXCR2… (More)

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@article{Sparer2004ExpressionOH, title={Expression of human CXCR2 in murine neutrophils as a model for assessing cytomegalovirus chemokine vCXCL-1 function in vivo.}, author={Tim Sparer and Jennifa Gosling and Thomas Schall and Edward S. Mocarski}, journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research}, year={2004}, volume={24 10}, pages={611-20} }