Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells.

@article{Noguchi1999ExpressionOH,
  title={Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells.},
  author={Hajime Noguchi and Choitsu Sakamoto and Ken Wada and Takuji Akamatsu and Tatsuo Uchida and Atsushi Tatsuguchi and Hirofumi Matsui and Hirokazu Fukui and Takahiro Fujimori and Masato Kasuga},
  journal={Gastroenterology},
  year={1999},
  volume={117 5},
  pages={1119-27}
}
BACKGROUND & AIMS Heregulins (HRGs) regulate the proliferation and differentiation of various cell types. However, very little is known about their function in the gastrointestinal tract. The aim of this study was to investigate the role of HRGs on gastrointestinal cells. METHODS We examined the expression of erbB receptors and HRG-alpha in human gastric cancer cell lines, rat gastrointestinal epithelial cells, and human gastric fibroblasts by Western blot analysis or reverse-transcription… CONTINUE READING

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