Expression of hemidesmosomes and component proteins is lost by invasive breast cancer cells.

@article{Bergstraesser1995ExpressionOH,
  title={Expression of hemidesmosomes and component proteins is lost by invasive breast cancer cells.},
  author={Lynn M. Bergstraesser and Ganesan Srinivasan and Jonathan C R Jones and Simone Stahl and Sigmund A. Weitzman},
  journal={The American journal of pathology},
  year={1995},
  volume={147 6},
  pages={1823-39}
}
Hemidesmosomes are multiprotein structures that attach basal cells of stratified epithelia to basement membranes. Although normal human breast epithelia are not stratified, we observed expression of electron-dense hemidesmosomes and hemidesmosome protein components by breast epithelial and myoepithelial cells at the basal lamina in vivo. Primary cultured normal human breast epithelial cells also contained hemidesmosomes and component proteins, and could be used as a model for hemidesmosome… CONTINUE READING

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