Expression of hbz mRNA promotes survival in HTLV-1-infected cells with high DNA damage

Abstract

Background HTLV1 may exert an initial pro-apoptotic stimulus via Tax-induced DNA damage. On the other hand, Hbz protein antagonizes some Tax effects on gene expression and hbz mRNA has been proposed as essential for maintaining oncogenesis. We hypothesize that expression of the hbz gene contributes to overcoming the pro-apoptotic signals in HTLV1 infected T… (More)
DOI: 10.1186/1742-4690-8-S1-A205

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Cite this paper

@inproceedings{Flores2011ExpressionOH, title={Expression of hbz mRNA promotes survival in HTLV-1-infected cells with high DNA damage}, author={Karina Flores and Giovanni M L{\'o}pez and Michael Talledo and Carolina Alvarez and E. Moreno Gonz{\'a}lez and Kristien Verdonck and Eduardo Gotuzzo and Daniel Clark}, booktitle={Retrovirology}, year={2011} }