Expression of glycodelin in MCF-7 breast cancer cells induces differentiation into organized acinar epithelium.

@article{Kmrinen1997ExpressionOG,
  title={Expression of glycodelin in MCF-7 breast cancer cells induces differentiation into organized acinar epithelium.},
  author={Meerit K{\"a}m{\"a}r{\"a}inen and Markku Sepp{\"a}l{\"a} and Ismo Virtanen and Leif C Andersson},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1997},
  volume={77 6},
  pages={565-73}
}
Glycodelin, a 28-kd human glycoprotein found in glandular epithelial cells of endometrium and seminal vesicle, was originally considered specific for the reproductive tract. Glycodelin has significant amino-acid sequence homology with beta-lactoglobulins from various species. We report herein the expression of glycodelin in normal and neoplastic glandular epithelia outside the reproductive tract including breast, sweat glands, parabronchial glands, hidradenoma, and pancreatic cystadenoma. The… CONTINUE READING

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