Expression of glycodelin and cyclooxygenase-2 in human endometrial tissue following three-dimensional culture.

@article{Esfandiari2007ExpressionOG,
  title={Expression of glycodelin and cyclooxygenase-2 in human endometrial tissue following three-dimensional culture.},
  author={Navid Esfandiari and Jafar Ai and Zohreh Nazemian and Murid H Javed and Lynda Gotlieb and Robert F. Casper},
  journal={American journal of reproductive immunology},
  year={2007},
  volume={57 1},
  pages={
          49-54
        }
}
PROBLEM Our previous study showed that in vitro culture of human endometrial tissue in a three-dimensional (3D) fibrin matrix could mimic the early stages of endometriosis with invasion, gland and stroma formation and sprouting of new vessels. The objective of the present study was to evaluate the expression of glycodelin (Gd) and cyclooxygenase-2 (COX-2), two angiogenic factors, to further validate the 3D culture model of endometriosis. METHOD OF STUDY Human endometrial fragments were… CONTINUE READING
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