Expression of glnA in Escherichia coli is regulated at tandem promoters.

@article{Reitzer1985ExpressionOG,
  title={Expression of glnA in Escherichia coli is regulated at tandem promoters.},
  author={Larry Reitzer and Boris Magasanik},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 7},
  pages={1979-83}
}
We have determined that the glnA gene of the complex glnALG operon of Escherichia coli is transcribed from tandem promoters. Expression from the upstream promoter, glnAp1, requires the catabolite activating protein, is repressed by nitrogen regulator I (NRI), the product of glnG, and produces a transcript with an untranslated leader of 187 nucleotides. Expression from the downstream promoter, glnAp2, requires NRI as well as the glnF product; full expression also requires growth in a nitrogen… CONTINUE READING