Expression of gec1/GABARAPL1 versus GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system.

@article{Nmos2003ExpressionOG,
  title={Expression of gec1/GABARAPL1 versus GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system.},
  author={Christophe N{\'e}mos and Virginie Mansuy and Sandrine Vernier-Magnin and Annick Fraichard and Mich{\`e}le Jouvenot and R{\'e}gis Delage-Mourroux},
  journal={Brain research. Molecular brain research},
  year={2003},
  volume={119 2},
  pages={216-9}
}
GABARAP and gec1/GABARAPL1 genes encode very similar proteins belonging to a new microtubule-associated protein (MAP) family. These proteins could participate in a complex clustering, targeting and/or degrading the GABA(A) receptors on post-synaptic membrane of neurons. Using specific cDNA probes, we investigated the differential expression of both genes in 76 human tissues. Against all odds, gec1/GABARAPL1 was more expressed than GABARAP in the central nervous system (CNS), while GABARAP was… CONTINUE READING