Expression of fatty acid binding proteins is altered in aged mouse brain

  title={Expression of fatty acid binding proteins is altered in aged mouse brain},
  author={Lixia Pu and Urule Igbavboa and G. K. Wood and John B. Roths and Ann B. Kier and Friedrich Spener and Friedhelm Schroeder},
  journal={Molecular and Cellular Biochemistry},
Brain membrane lipid fatty acid composition and consequently membrane fluidity change with increasing age. Intracellular fatty acid binding proteins (FABPs) such as heart H-FABP and the brain specific B-FABP, detected by immunoblotting of brain tissue, are thought to be involved in fatty acid uptake, metabolism, and differentiation in brain. Yet, almost nothing is known regarding the effect of age on the expression of the cytosolic fatty acid binding proteins (FABPs) or their content in brain… CONTINUE READING
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