Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis.

@article{Agardh2011ExpressionOF,
  title={Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis.},
  author={Hanna E Agardh and Lasse Folkersen and Johan Ekstrand and Diana M Marcus and Jesper Swedenborg and Ulf Hedin and Anders Gabrielsen and Gabrielle Paulsson-Berne},
  journal={Journal of internal medicine},
  year={2011},
  volume={269 2},
  pages={200-10}
}
OBJECTIVE the molecular basis for atherosclerotic plaque vulnerability with high risk of plaque rupture and thromboembolism is complex. We investigated whether clinical estimates of plaque stability correlate with differentially expressed mRNA transcripts within the lesion. METHODS AND RESULTS endarterectomy samples from patients undergoing surgery for symptomatic and asymptomatic carotid stenosis were prospectively collected and clinical parameters recorded in the Biobank of Karolinska… CONTINUE READING