Expression of factor X and its significance for the determination of paramyxovirus tropism in the chick embryo.

@article{Ogasawara1992ExpressionOF,
  title={Expression of factor X and its significance for the determination of paramyxovirus tropism in the chick embryo.},
  author={Takashi Ogasawara and Bin Gotoh and Hiroshi Suzuki and J Asaka and Kaoru Shimokata and Rudolf Rott and Yoshiyuki Nagai},
  journal={The EMBO journal},
  year={1992},
  volume={11 2},
  pages={467-72}
}
Enveloped animal viruses usually possess a surface glycoprotein which mediates fusion between the viral envelope and host cell membrane, hence enabling the initiation of infection, and its biosynthesis often involves post-translational endoproteolytic activation of the inactive precursor by a host cell protease(s). Therefore, the protease distribution in the host must be critical for determining the viral tropism. We previously isolated from chick embryo a cogent candidate endoprotease of this… CONTINUE READING

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