Expression of extracellular matrix-degrading metalloproteinases by cultured human cytotrophoblast cells: effects of cell adhesion and immunopurification.

@article{Bischof1991ExpressionOE,
  title={Expression of extracellular matrix-degrading metalloproteinases by cultured human cytotrophoblast cells: effects of cell adhesion and immunopurification.},
  author={Paul Bischof and E Friedli and M. Martelli and A de P Campana},
  journal={American journal of obstetrics and gynecology},
  year={1991},
  volume={165 6 Pt 1},
  pages={1791-801}
}
In vitro, invasion of basement membrane by human trophoblast can be blocked by metalloproteinase inhibitors. The purpose of our study was to characterize these enzymes by zymography, to define their cellular origin. First-trimester cytotrophoblast cells were prepared according to the method of Kliman et al. Half of the cell suspension was further purified… CONTINUE READING