Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia.

@article{Smith2001ExpressionOE,
  title={Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia.},
  author={Robert E. Smith and Vahram Haroutunian and Kenneth L. Davis and James H. Meador-Woodruff},
  journal={The American journal of psychiatry},
  year={2001},
  volume={158 9},
  pages={1393-9}
}
OBJECTIVE Recent investigations of schizophrenia have targeted glutamatergic neurotransmission, since phencyclidine, an N-methyl-D-aspartate (NMDA) receptor antagonist, can induce schizophreniform psychosis. The authors previously reported alterations in thalamic NMDA receptor subunit expression in schizophrenia, consistent with the hypothesis that thalamic glutamatergic hypofunction may contribute to the pathophysiology of this illness. In this study they generalized this hypothesis to include… CONTINUE READING

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