Expression of ets-1 transcription factor is correlated with penetrating tumor progression in patients with squamous cell carcinoma of the esophagus.

@article{Saeki2000ExpressionOE,
  title={Expression of ets-1 transcription factor is correlated with penetrating tumor progression in patients with squamous cell carcinoma of the esophagus.},
  author={Hiroshi Saeki and Hiroyuki Kuwano and H Kawaguchi and Satoshi Ohno and Keizo Sugimachi},
  journal={Cancer},
  year={2000},
  volume={89 8},
  pages={1670-6}
}
BACKGROUND The Ets-1 transcription factor is proposed to play a role in tumor invasion. To evaluate the biologic significance of Ets-1 in the progression of squamous cell carcinoma of the esophagus, the authors investigated Ets-1 expression in tumors from 90 patients using immunohistochemical procedures. METHODS The Ets-1 positive ratio (Ets-1 ratio) was determined in the center and deep margin areas of invasive sites and in the center and outer edge areas of intraepithelial spread contiguous… CONTINUE READING
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