Expression of estrogen receptor alpha and beta in myometrium of premenopausal and postmenopausal women.

@article{Sakaguchi2003ExpressionOE,
  title={Expression of estrogen receptor alpha and beta in myometrium of premenopausal and postmenopausal women.},
  author={Hideki Sakaguchi and Jiro Fujimoto and Ikumi Aoki and Teruhiko Tamaya},
  journal={Steroids},
  year={2003},
  volume={68 1},
  pages={11-9}
}
Although a clear role for estrogen receptor (ER) alpha has been established, the contribution of ERbeta in estrogen-dependent development, growth and functions of the myometrium is not understood. As a first step towards understanding the role of ERbeta, we have examined the expression of ERalpha and ERbeta in the human myometrium. With competitive RT-PCR assays, the level of ERbeta mRNA was 10-200 times lower than that of ERalpha mRNA in both premenopausal and postmenopausal myometrium. In… CONTINUE READING

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