Expression of endothelial nitric oxide synthase in the vascular wall during arteriogenesis

  title={Expression of endothelial nitric oxide synthase in the vascular wall during arteriogenesis},
  author={Wei-jun Cai and Elisabeth Kocsis and Xuegang Luo and Wolfgang Schaper and Jutta Schaper},
  journal={Molecular and Cellular Biochemistry},
Nitric oxide (NO) has been demonstrated to play an important role in angiogenesis, and also to be involved in collateral vessel growth. The expression of endothelial NO synthase (eNOS) is moderated partly by blood flow-induced mechanical factors, i.e., shear stress. The purpose of this study was to evaluate how the expression of eNOS correlates with the development of collateral vessels in dog heart, induced by chronic occlusion of the left circumflex artery. Immunoconfocal microscopy using an… CONTINUE READING


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