Expression of endothelial cell adhesion molecules in joints and heart during Borrelia burgdorferi infection of mice.

@article{Schaible1994ExpressionOE,
  title={Expression of endothelial cell adhesion molecules in joints and heart during Borrelia burgdorferi infection of mice.},
  author={Ulrich Emil Schaible and Dietmar Vestweber and Eugene Butcher and Thomas Stehl{\'e} and Markus Michael Simon},
  journal={Cell adhesion and communication},
  year={1994},
  volume={2 6},
  pages={465-79}
}
The expression of adhesion molecules on endothelia was examined during chronic arthritis and carditis in SCID and immunocompetent susceptible AKR/N mice infected with Borrelia burgdorferi (B. burgdorferi). All stages of disease were associated with the upregulation or new expression of ICAM-1 and P-selectin and of VCAM-1 and E-selectin, respectively, on blood vessels of affected joint tissues of SCID and AKR/N mice as well as on heart tissue of SCID mice but not in other tissues. Moreover, ICAM… CONTINUE READING