Expression of distinct RNAs from 3′ untranslated regions

  title={Expression of distinct RNAs from 3′ untranslated regions},
  author={Tim R. Mercer and Dagmar Wilhelm and M. Dinger and Giulia Sold{\`a} and Darren Korbie and Evgeny A. Glazov and Vy Truong and Maren Schwenke and Cas Simons and Klaus Ingo Matthaei and Robert B. Saint and Peter Koopman and John S. A. Mattick},
  journal={Nucleic Acids Research},
  pages={2393 - 2403}
The 3′ untranslated regions (3′UTRs) of eukaryotic genes regulate mRNA stability, localization and translation. Here, we present evidence that large numbers of 3′UTRs in human, mouse and fly are also expressed separately from the associated protein-coding sequences to which they are normally linked, likely by post-transcriptional cleavage. Analysis of CAGE (capped analysis of gene expression), SAGE (serial analysis of gene expression) and cDNA libraries, as well as microarray expression… 

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