Expression of defensin, cecropin, and transferrin in Aedes aegypti (Diptera: Culicidae) infected with Wuchereria bancrofti (Spirurida: Onchocercidae), and the abnormal development of nematodes in the mosquito.

@article{Magalhaes2008ExpressionOD,
  title={Expression of defensin, cecropin, and transferrin in Aedes aegypti (Diptera: Culicidae) infected with Wuchereria bancrofti (Spirurida: Onchocercidae), and the abnormal development of nematodes in the mosquito.},
  author={Tereza Magalhaes and I{\^e}da Ferreira de Oliveira and Maria Alice Varjal de Melo-Santos and Claudia C. M. F. Oliveira and Catarina A Lima and Const{\^a}ncia Fl{\'a}via Junqueira Ayres},
  journal={Experimental parasitology},
  year={2008},
  volume={120 4},
  pages={364-71}
}
The temporal expression of defensin, cecropin and transferrin was assessed in Aedes aegypti naturally refractory to Wuchereria bancrofti upon infection with this worm, in parallel to analysis of filarial development in the insect. Compared to controls, transcription of defensin and cecropin was higher in infected mosquitoes as soon as 2h post infection and peaked before 48h. Transferrin transcription was higher in infected mosquitoes at 24h, and at 48h was almost leveled to controls. At 72h and… CONTINUE READING