Expression of cytoskeletal components in melanocytic skin lesions. An immunohistochemical study.

@article{Puches1991ExpressionOC,
  title={Expression of cytoskeletal components in melanocytic skin lesions. An immunohistochemical study.},
  author={R Puches and Josef Smolle and Edgar Rieger and Hans Peter Soyer and Helmut Kerl},
  journal={The American Journal of dermatopathology},
  year={1991},
  volume={13 2},
  pages={
          137-44
        }
}
The cytoskeleton is considered to be important for maintaining cell shape and facilitating cell movement. In the present study, the expression of cytoskeletal components is examined in benign and malignant melanocytic skin tumors. Paraffin sections of 75 cases (25 each of nevocellular nevus, primary malignant melanoma, and cutaneous metastases of malignant melanoma) were stained with antibodies to tubulin, myosin, actin, and vimentin using a three-step immunoperoxidase method. The staining… CONTINUE READING

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