Expression of cytokine-like genes JE and KC is increased during renal ischemia.

@article{Safirstein1991ExpressionOC,
  title={Expression of cytokine-like genes JE and KC is increased during renal ischemia.},
  author={Robert L. Safirstein and Judit 4 Megyesi and Subodh J. Saggi and Pat M. Price and Man-chiu Poon and Barrett J. Rollins and Mark B. Taubman},
  journal={The American journal of physiology},
  year={1991},
  volume={261 6 Pt 2},
  pages={F1095-101}
}
Both mitogenic and inflammatory phenomena accompany the renal response to ischemic injury. Previous studies have shown that several nuclear-binding members of the immediate early genes are prominently expressed after renal ischemia and may underlie the mitogenic response to such injury. We now report on the expression of JE and KC, other growth-factor-responsive genes that code for small secreted glycoproteins with cytokine-like properties, which may play a role in inflammation. The expression… CONTINUE READING
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