Expression of cytokine genes and presence of enteroviral genomic RNA in endomyocardial biopsy tissues of myocarditis and dilated cardiomyopathy

@article{Satoh1996ExpressionOC,
  title={Expression of cytokine genes and presence of enteroviral genomic RNA in endomyocardial biopsy tissues of myocarditis and dilated cardiomyopathy},
  author={Masanobu Satoh and Ikuo Segawa and Atsushi Tashiro and Katsuhiko Hiramori and Gen Tamura and Ryoichi Satodate},
  journal={Virchows Archiv},
  year={1996},
  volume={427},
  pages={503-509}
}
Viral infection, especially by enteroviruses, has been considered to be the most common cause of myocarditis, which may progress to dilated cardiomyopathy (DCM). Although the mechanism of progression remains uncertain, a cytokine-associated injury of myocytes has been proposed. Using reverse transcriptase polymerase chain reaction (RT-PCR), we examined the expression of interleukin 1β (IL-1β), IL-6, IL-8 and tumour necrosis factor alpha (TNF-α) and the presence of enteroviral genomic RNA in… CONTINUE READING
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