Expression of cytokeratin 20 redefines urothelial papillomas of the bladder.

@article{Harnden1999ExpressionOC,
  title={Expression of cytokeratin 20 redefines urothelial papillomas of the bladder.},
  author={Patricia M Harnden and N Mohd Zaki Nik Mahmood and Jennifer Southgate},
  journal={Lancet},
  year={1999},
  volume={353 9157},
  pages={974-7}
}
BACKGROUND Most non-invasive urothelial tumours of the bladder are diagnosed as papillary carcinomas in accordance with the WHO classification and because the identification of papillomas is difficult by routine histology; some patients are therefore misdiagnosed. This practice is associated with psychological morbidity for the patient and may also skew cancer statistics. Cytokeratin 20 (CK20) is a sensitive marker of urothelial differentiation. We investigated whether this marker could be used… CONTINUE READING

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