Expression of cytochrome P4502E1 in human liver: Relationship between genotype and phenotype in Chinese

@article{Tan2001ExpressionOC,
  title={Expression of cytochrome P4502E1 in human liver: Relationship between genotype and phenotype in Chinese},
  author={Wen Tan and Jianxiong Wu and Huaijing Tang and Dong-xin Lin},
  journal={Science in China Series C: Life Sciences},
  year={2001},
  volume={44},
  pages={356-364}
}
Polymorphic cytochrome P4502E1 (CYP2E1) plays an important role in the metabolic activation of many carcinogens. We have previously shown that the c1/c1 genotype recognized byRsa I in the 5′-regulatory region of theCYP2E1 may be a susceptibility factor for developing esophageal cancer and lung cancer in Chinese. The present study was to investigate the relationship between theRsa I genotype and the expression of CYP2E1 in human livers. A total of 50 liver specimens were genotyped forCYP2E1 and… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Cytochrome P 450 2 E 1 genotype and chlorzoxazone metabolism in health and alcoholic Caucasian subjects

  • D. Lucas, C. Menez, C. Girre
  • Pharmacogenetics
  • 1995

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