Expression of cystic fibrosis transmembrane conductance regulator in human gallbladder epithelial cells.

@article{DrayCharier1995ExpressionOC,
  title={Expression of cystic fibrosis transmembrane conductance regulator in human gallbladder epithelial cells.},
  author={Nathalie Dray-Charier and Annick Paul and Danielle Veissi{\`e}re and Martine Mergey and Jean Yves Scoazec and Jacqueline Capeau and Christiane Brahimi-Horn and Chantal Housset},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1995},
  volume={73 6},
  pages={
          828-36
        }
}
BACKGROUND Hepatobiliary complications in cystic fibrosis result predominantly from lesions of the biliary epithelium. These abnormalities affect the intrahepatic as well as extrahepatic bile ducts and the gallbladder. The protein cystic fibrosis transmembrane conductance regulator (CFTR), the gene product defective in cystic fibrosis, functions as a cAMP-activated chloride channel in the plasma membrane. As such, it may represent an important driving force for fluid transport across the… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 15 CITATIONS

Functions of the Gallbladder.

VIEW 30 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

CFTR, mucins, and mucus obstruction in cystic fibrosis.

  • Cold Spring Harbor perspectives in medicine
  • 2012
VIEW 2 EXCERPTS
CITES BACKGROUND

Tissue and cellular expression patterns of porcine CFTR: similarities to and differences from human CFTR.

  • The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • 2010
VIEW 1 EXCERPT
CITES BACKGROUND

Electrogenic bicarbonate secretion by prairie dog gallbladder.

  • American journal of physiology. Gastrointestinal and liver physiology
  • 2007
VIEW 1 EXCERPT
CITES RESULTS