Expression of cyclooxygenase-2 in primary and remnant gastric carcinoma: comparing it with p53 accumulation, Helicobacter pylori infection, and vascular endothelial growth factor expression.

@article{Kawabe2002ExpressionOC,
  title={Expression of cyclooxygenase-2 in primary and remnant gastric carcinoma: comparing it with p53 accumulation, Helicobacter pylori infection, and vascular endothelial growth factor expression.},
  author={Atsushi Kawabe and Yutaka Shimada and Shigeki Uchida and Masato Maeda and Seiji Yamasaki and Masayuki Kato and Yosuke Hashimoto and Gakuji Ohshio and Masao Matsumoto and Masayuki Imamura},
  journal={Journal of surgical oncology},
  year={2002},
  volume={80 2},
  pages={79-88}
}
BACKGROUND AND OBJECTIVES Cyclooxygenase-2 (COX-2) expression may contribute to the synthesis of prostanoids, which have been related to carcinogenesis and tumor progression. It is well known that the gastric remnant is at greater risk of the development of gastric cancer than is the whole stomach; incidence rates for gastric cardia adenocarcinoma are rising in the United States and Europe. Our objective was to determine the involvement of COX-2 in primary and remnant gastric cancer tissues as… CONTINUE READING
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