Expression of cyclooxygenase-2 in normal urothelium, and superficial and advanced transitional cell carcinoma of bladder.

@article{Margulis2007ExpressionOC,
  title={Expression of cyclooxygenase-2 in normal urothelium, and superficial and advanced transitional cell carcinoma of bladder.},
  author={Vitaly Margulis and Shahrokh F Shariat and Raheela Ashfaq and Melissa G Thompson and Arthur I. Sagalowsky and Jer-Tsong Hsieh and Yair Lotan},
  journal={The Journal of urology},
  year={2007},
  volume={177 3},
  pages={1163-8}
}
PURPOSE We compared the differential expression of cyclooxygenase-2 in normal bladder tissue, primary bladder transitional cell carcinoma and transitional cell carcinoma metastases to lymph nodes, and determined whether cyclooxygenase-2 expression is associated with molecular alterations commonly found in bladder transitional cell carcinoma and clinical outcomes after radical cystectomy. MATERIALS AND METHODS Immunohistochemical staining for cyclooxygenase-2, survivin (Novus Biologicals… CONTINUE READING

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