Expression of cyclooxygenase-2 in colorectal cancer and its clinical significance

  title={Expression of cyclooxygenase-2 in colorectal cancer and its clinical significance},
  author={Bin Xiong and Tingting Sun and Weidong Hu and F. Cheng and Min Mao and Yun-feng Zhou},
  journal={World journal of gastroenterology},
  volume={11 8},
AIM To clarify the clinicopathologic significance of COX-2 expression in human colorectal cancer. METHODS A total of 128 surgically resected colorectal cancer specimens were immunohistochemically analyzed with the use of anti-COX-2, anti-VEGF and anti-MMP-2 antibodies. The relationship between the cyclooxygenase-2 expression in primary lesions of colorectal cancer and clinicopathologic parameters was evaluated by chi-square test. RESULTS Among 128 cases of colorectal cancer, 87 (67.9%) were… CONTINUE READING
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