Expression of cyclooxygenase-2 in chronic hepatitis B and the effects of anti-viral therapy.

@article{Cheng2002ExpressionOC,
  title={Expression of cyclooxygenase-2 in chronic hepatitis B and the effects of anti-viral therapy.},
  author={Alfred S. L. Cheng and H L-Y Chan and Nancy W. Y. Leung and Choong Tsek Liew and K F To and Paul B-S Lai and Joseph Jao Yiu Sung},
  journal={Alimentary pharmacology & therapeutics},
  year={2002},
  volume={16 2},
  pages={251-60}
}
BACKGROUND Cyclooxygenase-2 may play a role in the development of hepatocellular carcinoma, but the relationship between cyclooxygenase-2 and chronic hepatitis B is unknown. AIM To investigate the expression and cellular localization of cyclooxygenase-2 in chronic hepatitis B patients and the effects of anti-viral therapy. METHODS Using immunohistochemistry, in situ hybridization, Western blot and reverse transcription polymerase chain reaction, protein and messenger RNA expression and… CONTINUE READING

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