Expression of cyclooxygenase-2 in benign naevi and during human cutaneous melanoma progression.

@article{Kubicki2006ExpressionOC,
  title={Expression of cyclooxygenase-2 in benign naevi and during human cutaneous melanoma progression.},
  author={Lukasz Kuźbicki and Agnieszka Sarnecka and Barbara W. Chwirot},
  journal={Melanoma research},
  year={2006},
  volume={16 1},
  pages={29-36}
}
Cyclooxygenase-2 (COX-2) is an enzyme that plays an important role in the production of prostaglandins. Numerous studies have demonstrated increased levels of COX-2 in human cancers of different types. It is thought that COX-2 may be involved in the development and progression of malignant tumours. However, data on the changes in COX-2 expression during the development and progression of human melanoma are relatively limited. Moreover, the results reported by different groups disagree to a… CONTINUE READING
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