Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer.

@article{Hwang1998ExpressionOC,
  title={Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer.},
  author={Daniel H. Hwang and Deborah A. Scollard and Julianne Byrne and Ellis Levine},
  journal={Journal of the National Cancer Institute},
  year={1998},
  volume={90 6},
  pages={455-60}
}
BACKGROUND Numerous studies have demonstrated that the levels of prostaglandins are greater in various cancers, including breast cancer and colon cancer, than in normal tissues. In particular, the inducible form of cyclooxygenase (COX), the rate-limiting enzyme in prostaglandin biosynthesis, is overexpressed in colon tumors. Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the risk of colon cancer and, to a lesser… CONTINUE READING

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Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal anti - inflammatory drugs ( NSAIDs ) can reduce the risk of colon cancer and , to a lesser extent , the risk of breast cancer .
Numerous studies have demonstrated that the levels of prostaglandins are greater in various cancers , including breast cancer and colon cancer , than in normal tissues .
Surgical specimens from 44 patients with breast cancer who had undergone lumpectomy or mastectomy were analyzed by immunoblot analysis and immunohistochemical analysis to determine the expression profile of the constitutively expressed form of cyclooxygenase ( COX-1 ) and the inducible form ( COX-2 ) ; the specimens from 14 patients included normal breast tissue .
Surgical specimens from 44 patients with breast cancer who had undergone lumpectomy or mastectomy were analyzed by immunoblot analysis and immunohistochemical analysis to determine the expression profile of the constitutively expressed form of cyclooxygenase ( COX-1 ) and the inducible form ( COX-2 ) ; the specimens from 14 patients included normal breast tissue .
Surgical specimens from 44 patients with breast cancer who had undergone lumpectomy or mastectomy were analyzed by immunoblot analysis and immunohistochemical analysis to determine the expression profile of the constitutively expressed form of cyclooxygenase ( COX-1 ) and the inducible form ( COX-2 ) ; the specimens from 14 patients included normal breast tissue .
Surgical specimens from 44 patients with breast cancer who had undergone lumpectomy or mastectomy were analyzed by immunoblot analysis and immunohistochemical analysis to determine the expression profile of the constitutively expressed form of cyclooxygenase ( COX-1 ) and the inducible form ( COX-2 ) ; the specimens from 14 patients included normal breast tissue .
Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer . BACKGROUND .
Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer . BACKGROUND .
Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer . BACKGROUND .
Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer . BACKGROUND .
Numerous studies have demonstrated that the levels of prostaglandins are greater in various cancers , including breast cancer and colon cancer , than in normal tissues .
Surgical specimens from 44 patients with breast cancer who had undergone lumpectomy or mastectomy were analyzed by immunoblot analysis and immunohistochemical analysis to determine the expression profile of the constitutively expressed form of cyclooxygenase ( COX-1 ) and the inducible form ( COX-2 ) ; the specimens from 14 patients included normal breast tissue .
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